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The occlusion suture was left in place for 90 minutes

Strikingly, this oxidizing shift in the [NAD + ]/[NADH] induced by ketone ester treatment and the oxidizing shift in the total NAD + /NADH during a ketogenic diet were opposite to the reductive shifts that occurred in the hippocampus and cortex during fasting, as discussed above

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Certain unknown factors involved in the whole pathway should be further investigated