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Oxidative stress is essentially the damage that is done to the body when the amount of free radicals is higher than the number of antioxidants being produced by the body
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Elevated ROS levels disrupt antioxidant defenses, including glutathione peroxidase 4 (GPX4) activity and the cystine/glutamate antiporter system (xCT), thereby disturbing redox homeostasis and promoting lipid peroxidation and ferroptosis-related cellular damage
