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Selenoprotein T exerts an essential oxidoreductase activity that protects dopaminergic neurons in mouse models of Parkinsons disease

proceedings of the 4th International Conference Current Breakthrough in Pharmacy (ICB-Pharma 2022)

According to the significant reduction in anti-urease activity after adding sulfhydryl-containing reagents or competitive Ni 2+ -binding restrainers, sanguinarine (a natural alkaloid enriched in Zanthoxylum nitidum) is supposed to suppress urease by targeting Ni 2+ and thiol (Lu et al., 2022)