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doi: 10.1080/10837450.2021.1948571 [DOI] [PubMed] [Google Scholar] 132.ElShagea HN, Makar RR, Salama AH, Elkasabgy NA, Basalious EB
Consequently, dose optimisation for nose-to-brain delivery involves a balance between achieving a therapeutic concentration at the target site with minimal nasal irritation (Chung et al., 2023
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At the GLP-1 receptor, retatrutide is roughly eight times more potent than tirzepatide, so it engages more receptor per dose
