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Expert Rev Anticancer Ther 6 : 131140 Green MC, Buzdar AU, Smith T, Ibrahim NK, Valero V, Rosales MF, Cristofanilli M, Booser DJ, Pusztai L, Rivera E, Theriault RL, Carter C, Frye D, Hunt KK, Symmans WF, Strom EA, Sahin AA, Sikov W, Hortobagyi GN (2005) Weekly paclitaxel improves pathologic complete remission in operable breast cancer when compared with paclitaxel once every 3 week

690 Bioinformatics analysis and qPCR results of rat spinal cord tissue showed that mRNA levels of PTGS2, JUN, RELA, ATF3, TLR4, HMOX1, and STAT3 were upregulated, while mRNA levels of MAPK9, MAPK1, and VEGFA were downregulated

doi: 10.1016/j.biopha.2018.03.031 99 BarbieriFBosioAGPattarozziATonelliMBajettoAVerduciIet al

These mediators can compromise the integrity of the BBB, allowing the entry of viruses and cytokines into the CNS and activating brain immune cells, resulting in neuroinflammation [48,51,52,53]
