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3-AB is an early discovered PARP inhibitor, and its specificity is lower than newer PARP inhibitors developed for clinical use 176

Antioxidants help fight free-radical molecules

For example, omega-3 fatty acids have been shown to reduce oxidative stress in vivo by enhancing endogenous antioxidant defenses, as evidenced by increased total antioxidant capacity and glutathione peroxidase activity, together with decreased lipid peroxidation markers malondialdehyde (MDA) in clinical trials [115]

Acknowledgements are also to the support of the Swedish Research Council (202302216), the Strong Research Environment MultiPark (Multidisciplinary research on Parkinson's disease), Parkinsonfonden (1494/2023), the Innovation and Entrepreneurship Training Program for China Medical University Students (No