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Description
Its effects span virtually every organ system: it promotes longitudinal bone growth (epiphyseal plates), stimulates protein synthesis in skeletal muscle, mobilizes fatty acids from adipose tissue, and maintains immune function and organ homeostasis
Determinant roles of renal failure and drug accumulation
The primary risk is wasting money on poorly absorbed formulations that dont reach therapeutic plasma levels
Several in-vitro and in-vivo studies confirmed important effect of PEGylation on NP biodistribution, stabilization, and structure [20, 30,31,32]
