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Rights and permissions Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited

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Oxidative DNA damage can lead to global hypomethylation or locus-specific changes [49,50,51,52,53], while histone modification, such as reduced H3K4 methylation and altered acetylation of H3 and H4 residues affect the expression of genes controlling antioxidant defense and mitochondrial function [54,55,56,57,58,59]

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Archives of Pharmacal Research , 30(7), 834839

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Papillary thyroid carcinoma: a malignant tumor with increased antioxidant defense capacity

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