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Performance assessments were conducted using a cycling ergometer test lasting 13 min, during which respiratory quotient, heart rate, and perceived exertion (Borg scale) were recorded at 1-min intervals
According to another study, in HFD-induced MASLD mice model, the downregulation of methyltransferase-like 14 (METTL14) decreased glutaminase 2 (GLS2) protein levels by reducing N6-methyladenosine (m6A) modification of GLS2 mRNA, which exacerbated oxidative stress in the liver

doi: 10.1089/lap.2020.0878.Epub 2020 Dec 21 Larry Benjamin, Laura J Wood, Jasleen K Jolly, Markus Groppe, James F Kirwan, Nishal Patel, Mostafa A Elgohary, Robert E MacLaren

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