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Reports of severe adverse events include allergic reactions ranging from mild rashes to anaphylactic shock, kidney dysfunction particularly with high doses or prolonged use, liver toxicity in susceptible individuals, and thyroid dysfunction affecting hormone regulation

But what are the best ways to study this diverse group of molecules and the cascade of signaling events that ensue in the cell

doi: 10.1016/bs.afnr.2017.11.003 170

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