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According to previous studies, reperfusion can reduce cardiac function and is associated with an increased risk of HF (Yu et al., 2021)
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10.1111/nph.12303 New Phytol
In a cohort including simple nevi, dysplastic nevi, primary malignant melanomas, and metastatic lesions, immunohistochemical analyses revealed significantly increased 4-HNE levels in dysplastic nevi compared to benign nevi while remaining stable in cutaneous malignant melanoma and markedly reduced in metastases
