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Research / Wellness Peptides | No Adequate Long-Term Human Safety Data BPC-157: All safety data from animal models
10.1371/journal.pone.0096969 39 ChenH.ZhangF.LiR.LiuY.WangX.ZhangX.et al (2020)

DOX-induced nephropathy is a classic model of renal failure in rats
Eight weeks of methyl-donor supplementation at 4 weeks of age in female rats reduced oxidative stress, as measured by the nitrite content in the rat hippocampus, reduced anxiety-like behavior in the elevated plus maze test, and depressive-like behavior in the forced swimming test, reinforcing the notion that methyl donors could act as nutri-therapeutic agents in mitigating the effects of stress-related disorders such as anxiety and depression [133]
