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The CellChat analysis showed an increase in tumor and myeloid cell interactions as well as a decrease in CD8 T cell and tumor cells interactions in the postNI liver metastases compared with baseline (Supplementary Fig

detection Kit, Vector Laboratories, Inc.) were used for IHC following the manufacturers instructions

score 3: more than 50% irregular vascularization: increased number of capillaries, groups of thick-walled blood vessels irregularly arranged in the hypercellular tendon, and a nodular proliferation of blood vessels that can also be vertically directed in relation to their counterpart fibers

An optimal effect may also require a decrease in body fat to prevent the conversion of estrogens to androgens by adipose tissue [10]