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Materials and methods Generation of adipocyte-specific SIRT3 overexpression mice The environmental conditions in the animal facility were: temperature range of 2123 C, humidity range of 4050%, 12 h light/dark cycle, and free access to food and water

Offspring, which is compound heterozygous for the leptin receptor defect, develops the obese phenotype (O-ZSF1), and eventually HFpEF

Most women start noticing improvements in cycle regularity, energy or ovulation signs after 13 months of consistent use, because egg maturation takes about 90 days

Since 1921, ketogenic diet (KD) therapy has been a recognized effective tool in the treatment of epilepsy