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Since vitamin B 12 is a determinant of homocysteine metabolism, it was suggested that the risk of osteoporotic fractures in older subjects might be enhanced by vitamin B 12 deficiency

High hepatic fat content is the important inducement of the impairment of redox imbalance and insulin resistance

O 2 can reduce ferric iron (Fe 3+ ) to Fe 2+ , which suggests that it can play two roles in producing OH

10.1016/j.cell.2025.03.005 258 LeeH.-J.LeeK.-E.KimJ.-K.KimD.-H