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Common reasons include: Pernicious anemia , an autoimmune condition affecting intrinsic factor production Gastrointestinal disorders, such as Crohns disease or celiac disease Prolonged use of certain medications, like proton pump inhibitors Knowing these causes helps spot at-risk people

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Both the inactive form of vitamin D, 25- dihydroxy vitamin D [25(OH) 2 D], and the active form of vitamin D, 1,25-dihydroxyvitamin D [1,25(OH) 2 D], play an essential role in reducing inflammation and intracellular oxidative stress [124]

A number of factors contribute: Different manufacturers use different stabilization/packaging processes (e.g., presence of excipients, vacuum sealing, desiccants)
