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Targeted disruption of glutathione peroxidase 4 in mouse skin epithelial cells impairs postnatal hair follicle morphogenesis that is partially rescued through inhibition of COX-2

Whereas creatinine-based estimates of GFR are able to predict risks associated with declining kidney function when eGFR levels fall to 60 mL/min/1.73m2 or less, GFR estimates based on cystatin C level are predictive at approximately 85 mL/min/1.73m2

Mitochondrial glutathione neutralizes these free radicals before they damage mitochondrial DNA and membranes

Milella M, Konopleva M, Tabe Y, Precupanul C, Gregorj C, Carter BZ, Kornblau SM , Cognetti F, Tafuri A, Andreeff M