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Indeed, the downexpression of GLAST or GLT-1 increased extracellular glutamate levels in the CNS, while that of EAAC1 did not affect the levels [105]

A., Feng, D., Brown, L

Advanced metabolic imaging techniques, particularly hyperpolarized MRI for real-time flux assessment and multi-tracer PET for comprehensive metabolic profiling, will enable non-invasive patient stratification and response monitoring

The oxaliplatin-resistant OVCAR8 cell line (OVCAR8/OxR) was generated by treating the OVCAR8 human ovarian cancer cell line repeatedly with increasing concentrations of oxaliplatin until at least a 10-fold increase in IC 50 was observed