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This was a recommendation both in the James Lind Alliance Priority Setting Partnership which PAS initiated and funded and in the NICE Guideline on B12 Deficiency which PAS initiated

Given the many unknowns with high dose folic acid supplementation, particularly unmetabolized folic acid (as covered in my folate article), Im not able to draw any strong conclusions here

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The boosted energy levels from B12, combined with the enhanced fat metabolism from the MIC complex, help patients maintain the energy and motivation needed to stay consistent with their lifestyle changes