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Description
Amylin, released from beta cells in the pancreas, induces its satiating effect via both the homoeostatic and hedonic regions of the brain

Data shows that 48% of members using these drugs for weight loss stop therapy prematurely, a rate significantly higher than the 33% discontinuation rate seen among diabetes patients

Currently, NICE-approved pharmaceutical options include orlistat (a lipase inhibitor) and, more recently, semaglutide (Wegovy) for specific patient groups meeting eligibility criteria

2024;143 doi: 10.1016/j.intimp.2024.113537
