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The search for GLP- 1 receptor agonists to treat T2DM was sparked by studies showing the insulinotropic and glucose-lowering effects of GLP- 1 in beta cells, as well as the hyperglycemic effects of GLP- 1 receptor antagonism [44]

Reducing weight by 5 % or more significantly improves obesity-related health complications [7]

In contrast, the injection of GLP-1 and Ex4 into the OB of WD mice normalised the time course of glycaemia during OGTT to a value close to that of control RD mice (Fig
She is now taking a GLP1RA that has made transformative difference in her weight (she lost 20 pounds over two months) and metabolic control
