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Chronic low-grade inflammation associated with obesity and insulin resistance may contribute to fatigue, though the direct relationship between reduced inflammation and energy levels requires further research

You should not take phentermine if you have a history of heart disease, stroke, congestive heart failure, or uncontrolled high blood pressure

[DOI] [PMC free article] [PubMed] [Google Scholar] 154.Leslie S., et al

Whether the molecule will remain so robust in humans is yet to be determined
