does glp 1 cause leg cramps GLP-1RA Essentials in Gastroenterology: Side Effect Management, Precautions for Endoscopy and Applications for Gastrointestinal Disease Treatment Can GLP-1s cause muscle aches?

[DOI] [PubMed] [Google Scholar] 9.Welsh J.A., Karpen S., Vos M.B

A subgroup of the PCOS-induced mice received liraglutide 0.2 mg/kg for 21 consecutive days (twice daily, s.c.), while the other subgroup was treated with saline injections twice daily

* For those taking Wegovy pill, 76% achieved 5% or greater body weight loss (from a baseline body weight of 235 lb) versus 31% taking placebo (from a baseline body weight of 231 lb)

Nav1.8 is known for its unique property of activating at more negative potentials compared to other voltage-gated sodium channels, which may underlie a hyperexcitable state in EECs (Akopian et al., 1996