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Description
Whilst it avoids the upper gastrointestinal effects of Saxenda, orlistat commonly causes oily stools, faecal urgency, and flatulence with discharge, particularly when dietary fat intake is high
Therefore, GLP-1RAs hold promise as a novel therapeutic approach for diabetic patients with reduced -cell mass, stimulating -cell proliferation and differentiation (Iqbal et al., 2021)
They are gut-hormonebased metabolic drugs first approved by the FDA in 2005 (exenatide) for type 2 diabetes, now widely used for obesity
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